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miR-122 has been well-known to play a role in liver physiology and to be suppressed in primary hepatocellular carcinoma (HCC) suggesting that miR-122 has a tumor suppressor role (Wang et al., 2012)

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For example, by focusing on just three different modes of aging in yeast cells, researchers found that the complex interactions among multiple complex pathways could be modelled mathematically, providing a better understanding of these landscape patterns in aging and allowing them to drive certain gene expression patterns that could optimize cell lifespan (84)

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