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We acknowledge the support of rsula Wyneken (Facultad de Medicina, Universidad de los Andes), Nicols Muoz (CiiB, Universidad de los Andes), and Jean Carol Arce (Doctorado en Biomedicina, Facultad de Medicina, Universidad de los Andes)

(2019) 3:Cd007506

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Copper delivery to copper-dependent enzymes including lysyl oxidase and superoxide dismutase is the mechanism most commonly proposed to link these observations