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For example, many biologic drugs like Remicade and Imuran that are used to treat IBD come with black box warnings because they significantly increase the risk of infection and even death
In two phase 3 clinical trials involving more than 1,200 premenopausal women, PT-141 (bremelanotide) was shown to significantly improve sexual desire and reduce distress related to low desire compared with placebo ( Kingsberg et al., 2019, Obstetrics & Gynecology )