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In the six studies evaluated, when the change in pain intensity was the primary outcome, there was no statistically significant difference between the treatment and the placebo groups

ATLANTIC-DIP: Prevalence of metabolic syndrome and insulin resistance in women with previous gestational diabetes mellitus by International Association of Diabetes in Pregnancy Study Groups criteria

Some studies include only people with diabetes, while others include weight management patients who may have fewer baseline risk factors

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In summary, E2 has the potential to modulate apoptosis, thereby improving the functional status of tissues and organs in patients with OSAHS