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Most patients were managed on-site with poison center follow-up and not referred into a healthcare facility, likely due to the large number of double doses that remained within a therapeutic dosing range (Table 3)

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PT-141 was developed from Melanotan II and was originally intended to darken skin pigmentation and induce tanning

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Although these trials primarily enrolled individuals with relatively low DKD risk and were not designed to evaluate kidney outcomes specifically, exploratory analyses consistently indicated slower kidney disease progression across diverse eGFR and albuminuria levels [39-44]

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