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However, a statistically-significant and dose-related increase in the incidence of pancreatic adenomas was observed in the male rats fed 4 or 8 mg/kg

Aqua, Butylene Glycol, Glycerin, 1,2-Hexanediol, p-Hydroxyacetophenone, Copper Tripeptide-1, Panthenol, Niacinamide, Sodium Hyaluronate, Allantoin, Hydrolyzed Sodium Hyaluronate, Acetyl Hexapeptide-8, Arginine, Xanthan Gum, Disodium EDTA, Carbomer, Triethanolamine

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The mean standard error of urine volume were 9.0 0.7 mL and 10.5 0.6 mL in urine samples of Iriomote cats and Tsushima leopard cats, respectively (Supplementary Table S1)

Previous studies have demonstrated that UPS affects the function of GMCs through AGES/RAGE, NF-B, Trim13/CHOP, Smurf1/TGR5, and Nrf2/ARE pathways