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Although neither of these trials specifically targeted CHE nor demonstrated a significant reduction in OHE, many of the enrolled patients were likely to have CHE, and the results of the LiveSMART trial suggest potential clinical benefits of CHE-directed therapy beyond OHE prevention

J., Weimer, T., Kronthaler, U., Lang, W

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doi: 10.1016/j.joms.2015.03.061 6 SolesBSWilsonALucasDRHeiderA