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10.1016/j.ctrv.2017.09.010 42 MillerK

Obinutuzumab, a fully humanized type II anti-CD20 monoclonal antibody that can induce extensive B-lymphocyte depletion, has been evaluated in clinical trials for SLE, particularly focusing on LN (122)

However, Margaret McCarthys lab has shown that drug-mediated inhibition of prostaglandin synthesis (as is accomplished by acetaminophen) in laboratory rats during a time sensitive window in early postnatal life not only results in significant long-term modifications to brain development and morphology but also leads to decreased social interactions and reduced sensory function in male but not female animals