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22, 23 However, the core structure and function of the TJ depends on 50 discrete membrane-integral and -associated proteins located between the apical and lateral regions of the polarized epithelial cells

It is suggested that NPs have a greater risk of toxicity than the corresponding bulk (Hoet et al., 2004)

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These symptoms are often motor abnormalities associated with cerebellar or extrapyramidal injury.26 They may include tremor, coordination defects, dystonia, or choreiform movements.2729 Sensory function and intelligence are generally unaffected in Wilsons disease

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