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Conversely, in the fasted or low-energy state, falling leptin levels relieve the tonic inhibition on AgRP/NPY neurons while simultaneously failing to activate POMC neurons

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Kavin Panneerselvam from the Kasturba Medical College in Mangalore, and Sundaram Kumaran from the University of Madras in India, gave L-carnitine and alpha-lipoic acid separately or together to young, middle aged, and older rats