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Sleep apnea occurs when a persons upper airway becomes blocked while they snooze, causing pauses in their breathing that awaken them

This work was supported by the National Institutes of Health under award numbers 2R01HL115189, P30DK04056, UE5DK137285, and U24 DK132733, and by the National Clinician Scholars Program at the Duke Clinical and Translational Science Institute

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A triple combination therapy of liraglutide, metformin, and TZD for 26 weeks in 533 subjects (1:1:1) randomized to once-daily liraglutide (1.2 or 1.8 mg) or liraglutide placebo in combination with metformin (1 g twice daily) and rosiglitazone (4 mg twice daily) demonstrated significantly greater mean HbA1c values in the liraglutide groups versus placebo (mean SE, -1.5 0.1% for both 1.2 and 1.8 mg liraglutide and -0.5 0.1% for placebo)