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Thus, establishing whether the in vivo effect of leptin on macrophages favors atherogenesis in humans is of clinical interest, especially in diabetic patients who have elevated plasma leptin levels and demonstrate enhanced proatherogenic cytokines secretion by macrophages (e.g., tumor necrosis factor-

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Conditions such as type 2 diabetes, hypertension, sleep apnea, and cardiovascular disease can make someone a better candidate for these medications

Many medications, particularly biologics, may not work as well in patients carrying extra weight

Below, we outline several common sources of brain damage that can result in cerebral palsy