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Fat Loss Improves nutrient partitioning and stimulates fat burning

Long-term cardiovascular outcome studies are still underway, but interim data from trials like SUSTAIN-6 (semaglutide in type 2 diabetes) and SUMMIT (semaglutide in obesity without diabetes) showed sustained blood pressure benefits over months and years of treatment

Then there is the problem that we do not have reliable biomarkers to tell which patients are most likely to benefit

Quick Answer: Allulose may modestly increase endogenous GLP-1 secretion and could theoretically complement GLP-1 receptor agonist therapy, though robust clinical evidence for combined benefits is currently lacking

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