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J., Tobin, J., Stevens, T., Bellantoni, M

Once it has attached to the toxic molecules, glutathione helps make them water soluble so they can easily be flushed from the body

The first publications reported enzyme activity involving displacement of a halide ion from an aromatic compound, resulting in an S-substituted glutathione conjugate ( GSTs were first recognized as enzymes inactivating xenobiotics, in particular electrophilic mutagens and carcinogens, leading to their excretion as mercapturic acids ( An independent set of reports identified a remarkably abundant protein in liver with affinity for carcinogens, steroid hormones, bilirubin and synthetic dyes

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Side effects are generally mild most often injection site irritation, fatigue, or headache