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A responsible plan should include: medical supervision realistic goal-setting nutrition planning adequate protein resistance training or strength-focused movement hydration side-effect monitoring long-term maintenance planning emotional and behavioral support when needed Without that structure, people may lose weight but feel weak, undernourished, anxious about stopping, or unprepared for maintenance

Drygalski, K., et al

Donation centres prioritise donor safety and may defer individuals with active side effects

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They can evaluate the individuals overall health, discuss potential risks, and monitor for any adverse reactions during the course of the treatment