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Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix

In order to elucidate such mechanisms, the aim of this work was to study, in mice with partial IGF-1 deficiency, liver expression of genes involved in glucose and lipid metabolism as well as serum levels of glucose, triglycerides and cholesterol, as well as liver malondialdehyde (MDA) levels, as a marker for oxidative damage

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Hulmi, J

Interestingly however, all three variants are closely aligned within the so-called overlap region of the collagen fibril, in which molecules are staggered by multiples of D 37 (see Fig