For aesthetic enhancements, dermal fillers are a popular choice
Eyeliss (hesperidin methyl chalcone, dipeptide-2, and palmitoyl tetrapeptide-7 combination) specifically targets fluid retention dark circles through improving lymphatic drainage removing accumulated fluids, reducing capillary permeability decreasing fluid leakage into surrounding tissues, and anti-inflammatory effects minimizing puffiness-related darkness
and subsequent investigators has characterised GHK-Cu as a potent activator of wound-healing cascades, upregulating transforming growth factor- (TGF-) and suppressing inflammatory mediators such as TNF- and IL-6 in pre-clinical models
Boban-Blagaic A, Blagaic V, Romic Z, et al
The study noted potential regenerative effects on cartilage and suggested BPC-157 may reduce the need for surgical intervention in selected cases