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Sublingual B12, which bypasses the gastrointestinal tract, is the least invasive and potentially most cost-effective option, especially for individuals with impaired absorption, making it an attractive alternative for long-term and patient-friendly management (Vidal-Alaball et al., 2006)

Moreover, in patients with established gastroparesis, such as those with long-standing diabetes or critical illness, GLP-1 agonists did not significantly worsen gastric motility

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