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If numbness or tingling in the hands persists beyond 2 weeks, reduce the dose by 50% and reassess

Pleurotus pulmonarius laccase can transform 23% of AFB1 but the addition of 1 mM redox mediators, 2,2-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid, or acetosyringone resulted in an increased transformation of AFB1 to about 45% (Loi et al., 2016)

Acknowledgements We appreciate the statistical help of Paul Shragg and Reena Deutsch, PhD, of the NIH/NCRR-sponsored UCSD Clinical Research Center (MO1-RR00827)

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