STEP 1 enrolled over 1,900 adults without diabetes and showed an average weight loss of 14.9 percent of body weight over 68 weeks
767: Emergent therapy for acute-onset, severe hypertension during pregnancy and the postpartum period, Obstetrics and Gynecology (2019) DASH (Dietary Approaches to Stop Hypertension) dietary pattern and maternal blood pressure in pregnancy, Journal of Human Nutrition and Dietetics (2020) Guidelines for the prevention of stroke in women: A statement for healthcare professionals from the American Heart Association/American Stroke Association, Stroke (2014) Hydralazine hydrochloride drug summary, Prescribers Digital Reference Hypertension in pregnancy, StatPearls (2022) Hypertension in pregnancy and postpartum: Current Standards and opportunities to improve care, Circulation (2025) Hypertension in pregnancy: Diagnosis, blood pressure goals, and pharmacotherapy: A scientific statement from the American Heart Association, Hypertension (2022) Lupus-like syndrome in a mother and newborn following administration of hydralazine
One sailed through safety trials but stumbled on efficacy
Contraindicated in Leber's disease (B12 risk) 2
Once youve received a shot, the effects can last anywhere from a few days to a few weeks
