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The answer is bioavailability

Theyre fat-soluble, which means theyre absorbed into tissues and can accumulate in the body over time

Glutathione also keeps other antioxidants, like vitamins C and E, in their active form

(2020) who report the detection of almost all major ergot alkaloids (ergocornine, ergocorninine, ergocristine, ergocristinine, ergocryptine, ergocryptinine, ergometrine, ergometrinine, ergosine, ergosinine, ergotamine, ergotaminine) in urine as well as in serum samples from the EFCOVAL study, which covered individuals from Belgium, the Czech Republic, France, the Netherlands, and Norway