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doi: 10.1128/IAI.71.12.6754-6765.2003

Preclinical and early human data suggest GLP-1 RA signalling can suppress NF-Bdriven cytokine production, reduce macrophage M1 polarisation, and attenuate Th17 differentiation all pathways central to psoriatic disease

Compromised experiments and questionable data

Go AS, et al

Sodium-glucose cotransporter-2 (SGLT-2) inhibitor use was associated with reduced cardiovascular events and mortality compared to placebo in the Empagliflozin Cardiovascular Outcome Event Trial in Type 2 diabetes Mellitus Patients (EMPA-REG OUTCOME), CANagliflozin cardioVascular Assessment Study (CANVAS), and Dapagliflozin Effect on Cardiovascular Events Thrombolysis in Myocardial Infarction 58 (DECLARE-TIMI58) trials