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Can GLP-1 Medications Help MCAS, Fatigue, and More

Biochem 133 , 109707 (2024)

Among adults with a urine albumin-to-creatinine ratio of 30 mg/g or higher at baseline, those receiving tirzepatide 5 mg had a 31.3% greater urine albumin-to-creatinine ratio reduction, the tirzepatide 10 mg group had a 42.2% larger decline and the tirzepatide 15 mg group had a 47.3% greater decrease than adults in the pooled comparator group

Medium-term: oral dual agonists The success of orforglipron as a small-molecule GLP-1 agonist opens a pathway for small-molecule dual GIP/GLP-1 agonists

Potential side effects include GI upset, nausea and headache