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Global impact: Cataracts account for 51% of blindness worldwide, underscoring the potential global health impact of new antioxidant-based treatments

[DOI] [PubMed] [Google Scholar] Mogi M, Harada M, Riederer P, Narabayashi H, Fujita K, Nagatsu T (1994) Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients

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Xanthurenic acid, the major downstream metabolite of 3-HK capable of crossing the BBB, exhibits both antioxidant and pro-oxidant properties depending on experimental context [158, 161,162,163]

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