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Cross-comparison of mechanistic studies reveals frequent enrichment of canonical signaling axes including Wnt/-catenin, PI3K/AKT, VEGF/Notch, PDGF-BB, and HIF-1/VEGF

Abstract An anal fissure is a tear in the anoderm, typically in the posterior midline

J Neurosci Res 67:533543 Kimura S, Egashira K, Chen L, Nakano K, Iwata E, Miyagawa M, Tsujimoto H, Hara K, Morishita R, Sueishi K, Tominaga R (2009) Nanoparticle-mediated delivery of nuclear factor B decoy into lungs ameliorates monocrotaline-induced pulmonary arterial hypertension

Individuals with diabetes characterized by HbA1c 6.5%, or a history of surgical or device-based obesity treatment, were excluded