[13] In the first step of the reaction, acyl-CoA synthetase catalyzes the transfer of adenosine monophosphate group (AMP) from an ATP molecule onto the fatty acid generating a fatty acyladenylate intermediate and a pyrophosphate group (PP i )
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Clinically supervised topical use, with pharmaceutical-grade formulations, is the safest approach
Under these conditions, systemic metabolism increasingly relies on lipid-derived substrates and elevated oxidative throughput
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