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En definitiva, los frmacos GLP-1 representan una opcin prometedora para el tratamiento de diversas condiciones mdicas, desde la obesidad hasta enfermedades neurodegenerativas

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No one expected that it was going to shut down the progression of Alzheimers disease, but there was a hope that we would see some benefit, and we didnt. On supporting science journalism If you're enjoying this article, consider supporting our award-winning journalism by subscribing

It even cited the high cost of GLP-1 drugs, the class that includes Wegovy and Zepbound, as a key reason

Furthermore, the arrangement of COP1 WD40 domains sealed by layers of organization, suggests a potential unfavourable configuration for substrate ubiquitination