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For patients on hydrocodone bitartrate and acetaminophen tablets who are physically opioid-dependent, initiate the taper by a small enough increment (e.g., no greater than 10% to 25% of the total daily dose) to avoid withdrawal symptoms, and proceed with dose-lowering at an interval of every 2 to 4 weeks

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Scientists then isolated it and created a synthetic version to explore its benefits

Reuters first reported that the WHO was likely to take this step earlier this year

Always verify your pharmacy partners certifications before prescribing