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In landmark trials such as SUSTAIN-6 and PIONEER-6, semaglutide demonstrated a significant reduction in major adverse cardiovascular events, including cardiovascular death, non-fatal heart attacks, and strokes, compared to placebo or standard care

Generic manufacturers must complete FDA approval processes, including demonstrating bioequivalence to the original drug

For patients with insulin resistance or a semaglutide allergy, your doctor may suggest alternatives to GLP-1 anti-diabetic medications

Slower gastric motility causes retention of food and secretions in the stomach, increasing visceral sensory signaling that feels like fullness or queasiness, while central receptor activation can alter nausea thresholds

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