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If you experience severe, persistent abdominal pain (particularly if radiating to the back), this may indicate pancreatitisa rare but serious complication

Retatrutide reached 24.2% mean body-weight reduction at 12 mg/48 weeks in the Jastreboff et al

The resolution of this paradox likely involves dose, individual neurological vulnerability, and the difference between GLP-1 receptor activation in different nervous system compartments