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The glucagon receptor component is thought to contribute to increased energy expenditure, though this too is based largely on early clinical and preclinical observations rather than definitive human data

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Intermediate role of gut microbiota in vitamin B nutrition and its influences on human health

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Furthermore, a genetically determined increased expression of the TNF receptor 1 ( TNFRSF1A ) (rs4149570) 26 was associated with beneficial response among patients with CD and IBD