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With respect to mitochondrial parameters, dysfunction in one or more aspects of mitochondrial biology results in reduced oocyte developmental competence

Degradation of glutathione leads primarily to its constituent amino acids (e.g., cysteine, glycine), which can subsequently be used for glutathione synthesis inside the cell

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Emerging evidence indicates that flaviviruses, such as dengue virus and Zika virus (ZIKV), also target MAVS by promoting its ubiquitination and proteasomal degradation (Zhang et al., 2018)