The results showed much lower B12 concentrations in both healthy and affected tigers than in domestic cats, although reference ranges for serum cobalamin concentrations in tigers have not yet been established [56]
Among them, MAPKs, PI3K, PKC, ATM, AP-1, Sp-1, p53, and NFB have been reported to be involved in the activation of EBV replication [48,51,52,77,78]
In DFO-treated parasites, while some overlap with DHA-induced genes (e.g., merozoite-related functions) was observed at later stages, unique transcriptional changes were also evident, such as upregulation of genes involved in chromatin organization, protein-DNA complex assembly, nucleosome dynamics, regulation of RNA polymerase II-mediated transcription initiation, and regulation of protein catabolic processes
however, treatment decisions are dependent upon each individual and the patients care team
Almulla, A