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The latest in vitro and in vivo research results show that oxaliplatin-based oxidative stress enhance the phosphorylation level of serine residues of NFS1, which protect CRC cells in an S293 phosphorylation-dependent manner during oxaliplatin treatment ( Nuclear Protein 1 (NUPR1), a stress-inducible transcription factor, was identified as a driver of ferroptosis resistance through regulating Lipocalin 2 (LCN2) (Xiao et al., 2017)

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The Vagus nerve at the interface of the microbiota-gut-brain axis