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In these two Phase 3 studies (n=3,680 total), patients are randomized to placebo or oral semaglutide in a 1:1 ratio and assessed using the CDR-SB at 2 years, with follow-up of up to 3 years

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Additionally, uncontrolled hyperglycemia itself causes dry mouth through osmotic diuresis, though semaglutide's glucose-lowering effects should theoretically improve rather than worsen this symptom in patients with diabetes

Meanwhile, the European Medicines Agency (EMA) said this summer that Wegovy can also be used to prevent major cardiovascular problems like heart attacks and stroke among people with obesity

Mounjaro, on the other hand, is unique in that it targets metabolism instead of hunger signals, promoting weight loss by increasing the rate at which the body burns calories