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Genetic mapping of natural variation in insect resistance, mass spectrometry-based screens to identify previously unknown plant defensive metabolites, and characterization of biosynthetic enzymes through knockout mutations and in vitro enzyme assays have led to the discovery of novel plant defense mechanisms
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78 In the whole exome sequencing and whole transcriptome analysis of osteosarcoma, it was found that many genes were significantly differentially expressed between osteosarcoma and normal tissues
The intestinal microbiota of IBD patients is characterized by an increase in pro-inflammatory bacteria and altered expression of multiple cytokines [95, 97, 98]
Gahl WA, Bashan N, Tietze F, Bernardini I, Schulman JD (1982) Cystine transport is defective in isolated leukocyte lysosomes from patients with cystinosis
