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The studys results provide insights into some known and previously unrecognized benefits and risks of GLP-1RA that may be useful to inform clinical care and guide research agendas. The drugs, taken once a week by injection, simulate naturally produced hormones that curb appetite and slow digestion, creating longer-lasting satiety

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Takemoto K, Imai Y, Saito K, Kawasaki T, Carlton PM, Ishiguro K, Sakai N (2020) Sycp2 is essential for synaptonemal complex assembly, early meiotic recombination and homologous pairing in zebrafish spermatocytes

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BPC-157 was administered at doses of 10 g/kg, 1 g/kg, 100 ng/kg, and 10 ng/kg throughout the experiment, starting on day zero when therapy began, and daily during the trial periods of 7, 14, 21, 28, and 42 days