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Endpoints like memory and comprehension may represent damage to the brain that is irreversible, leading to disappointment in previous trials

Am J Physiol Lung Cell Mol Physiol 291 : L46L57 Hu S, Zhao H, Al-Humadi NH, Yin XJ, Ma JK 2006 Silica-induced apoptosis in alveolar macrophages: evidence of in vivo thiol depletion and the activation of mitochondrial pathway

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