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As the authors point out, these findings may help to explain why these metabolic abnormalities occur in a cluster (such as found in the metabolic syndrome), partly because people are exposed to low doses of various POPs simultaneously

The peptide does not appear to affect blood pressure, heart rate, or standard laboratory values in studied animal models

Previous research has indicated that projections from the ventral tegmental area (VTA) to the BLA are implicated in the regulation of anxiety-like behaviors [11], and that inflammation within the BLA can intensify anxiety and depressive behaviors in mice [12]

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Additionally, blockade of GLP-1Rs in the LS with exendin-9 alone enhanced sucrose and oil intake indicating a physiologic role for these neurons to suppress food intake