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The 2023 international PCOS guideline confirms letrozole as first-line for ovulation induction, with metformin recommended for adults with PCOS and BMI 25 kg/m for metabolic and anthropometric outcomes

Studies demonstrate capsaicinoids promote energy expenditure by approximately 50 calories per day, support fat burning, and reduce appetite by lowering energy intake

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Sermorelin peptides primarily stimulate natural growth hormone production