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Plasma activated oil: Fast production, reactivity, stability, and wound healing application

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Its active site is the sulfhydryl group on the cysteine residue, and that group is chemically vulnerable

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The reaction of ,-unsaturated carbonyl covalent inhibitors with KRAS G13C under physiological conditions likely occurs by a concerted mechanism involving proton transfer, nucleophilic addition, and solvent-assisted tautomerization 39