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Leading adenoviral vectors in SARS-CoV-2 clinical trials are adenovirus type 5 vector (Ad5-nCoV) as of 16 March 2020 and chimpanzee adenovirus vaccine vector (ChAdOx1) as of 31 March 2020 by CanSino Biological and the University of Oxford, respectively (Table 1)

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Arch Biochem Biophys 447(2):155166

showed that NAC (6001,000 mg/day) restored antioxidant balance and reduced inflammation, though without lung function improvement ( A phase II trial using high-dose NAC (2,800 mg/day, 12 weeks) increased sputum glutathione but did not affect inflammatory markers or lung function ( 1 decline (by 150 mL) versus placebo over 24 weeks, though primary endpoints were unmet due to underpowering ( Cystic fibrosis patients with chronic P

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