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The lack of adequate cobalamin in the body hinders the regeneration of tetrahydrofolate, which eventually leads to megaloblastic anemia due to the functional folate deficiency.On the other hand, the methylmalonyl-CoA mutase helps to metabolize odd chain fatty acids and branch chain amino acids.Cobalamin is also thought to keep the bodys level of sulfhydryl (SH) groups in reduced form

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doi: 10.3389/fneur.2025.1561000 Received 15 January 2025 Accepted 17 March 2025 Published 02 April 2025 Volume 16 - 2025 Edited by Claudia Altamura, Fondazione Policlinico Campus Bio-Medico, Italy Reviewed by Emel Ur Ozcelik, Istanbul University, Trkiye Adina Maria Roceanu, Bucharest University Emergency Hospital, Romania Updates Copyright 2025 Sun, Chen, Song, Gao and Xu

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