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Mimicking a natural hormone called glucagon-like peptide-1, semaglutide regulates blood sugar levels and works in the brain to induce the sensation of fullness, making the user eat less and curb appetite

However, this was a small study with significant limitations, and berberine is not a substitute for prescribed diabetes treatment or any other medical therapy

Most of that ended a couple days ago

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Front Cell Neurosci 17:1139357 Liang X et al (2022) Gut microbiome, cognitive function and brain structure: a multi-omics integration analysis