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doi: 10.3389/fphar.2020.579944 Received 03 July 2020 Accepted 15 September 2020 Published 07 October 2020 Volume 11 - 2020 Edited by Leonello Fuso, Catholic University of the Sacred Heart, Italy Reviewed by Stephen C

Figure 1 On this basis, this review summarizes the major regulatory mechanisms by which amino acid metabolism shapes macrophage polarization from the perspective of immunometabolic network integration, and further outlines the research progress in different autoimmune diseases