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Real-world versus clinical trial timelines Clinical trials represent controlled conditions

For those who were sick with obesity, but don't qualify for bariatric surgery, semaglutide provides a lot of hope, Rubino said

This was not only a benefit to diabetic patients, but also to those looking to lose weight

There were fewer serious safety events in the drug group than in the placebo group, although more patients stopped taking semaglutide, primarily because of gastrointestinal issues that are common side effects with this class of medicines, known as GLP-1 receptor agonists

Clinical trials for semaglutide began in the early 2010s, with the SUSTAIN phase 3 trial program enrolling patients starting in 2012