DPP-4 is also expressed in the renal proximal tubular brush border, where it regulates Na+/H 2 O reabsorption (97)
Until recently, it was thought they could, in rare cases, cause suicidal thoughts or actions for some people, though in 2024, the FDA conducted a preliminary but broad review that found no evidence that was true
Particle auto-picking was performed using a pretrained model in the crYOLO software package, followed by particle extraction in a box-size equivalent to 320 and Fourier down-sampled to 64 pixels
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Therefore, DEX-mediated increase in uric acid excretion is mainly due to the downregulation effect of URAT1 (Li et al., 2019)