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Table 3: Efficacy Endpoints in Study 2 Figure 3 displays the mean change from baseline in the average monthly number of headache days of at least moderate severity in Study 2

Site-Specific Irritation (IGF-1 DES) Localized injection into muscle tissue may cause irritation or redness

Protect from light and moisture Intended Use: For laboratory research use only

Some people can tolerate twice-daily use after their skin adjusts, but always listen to your skin and reduce frequency if you experience irritation

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