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Once you know the big pharmaceutical companies are spending a lot of money looking for glucagon receptor antagonists and testing them, and GIP receptor antagonists and testing them, it requires a lot of gusto, a lot of lunacy and craziness to say, nah, I believe all these big pharmaceutical companies are wrong, my lab is doing the opposite. But now, the sentiment has drastically shifted and many companies are looking to co-agonist drugs to achieve over 20%, or even close to 30% weight loss

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Participants were followed up for a total of 5 years post drug initiation

Higelin, J