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Research Context Potency: In preclinical studies, Dihexa was shown to be millions of times more potent than BDNF at stimulating synaptogenesis

Furthermore, SEMA was shown to lower the levels of the pro-inflammatory cytokines IL-1, IL-6, and TNF- in the blood as well as the levels of IL-1 and TNF- in the dorsal horn

In a clinical trial of semaglutide injection for weight loss (Wegovy) in patients with T2DM and a BMI of 27 kg/m2 or more, hypoglycemia (defined as a plasma glucose less than 54 mg/dL) was reported in 6.2% of semaglutide-treated patients versus 2.5% of placebo-treated patients

75 In addition, improved hearing by hearing aids may help reverse or normalize maladaptive brain activity in tinnitus sufferers, as well as reduce stress and anxiety by improving communication

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